HalotechDNA, based in Madrid and founded in 2008, is a leading biotechnology company dedicated to research, development and marketing of solutions in the field of fertility. Our in vitro diagnostic kits, together with support for medical professionals, are a reflection of the innovative and high quality effort we bring to our solutions.
Halosperm (REF: HT-HS10)
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Halosperm® allows for an improved evaluation of sperm quality, complementing the information offered by the conventional sperm analysis. Conventional semen analysis only studies spermatozoa concentration, motility and morphology. It is an incomplete study, as it omits analysis of one of the most important parameters, the integrity of the DNA molecule. 15% of men considered to be infertile present normal sperm analyses, which makes a deeper assessment of the sample important. Halosperm® facilitates decision-making for medical professionals regarding which assisted reproduction technique is most appropriate for each couple.
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Halosperm® is based on the SCD technique, patented by Halotech, based on a controlled DNA denaturation process to facilitate the subsequent removal of the proteins contained in each spermatozoon. In this way, normal spermatozoa create halos formed by loops of DNA at the head of the sperm, which are not present in those with damaged DNA.
The images of halos generated with Halosperm® are highly contrasted and can be evaluated precisely using conventional or fluorescent microscopy. The tails of the spermatozoa are preserved, so it is possible to discriminate them from other cell types that might be present in the ejaculate, such as leukocytes. In addition, Halosperm® allows the visualisation of spermatozoa that contain highly degraded DNA compared to other types of less aggressive damage. This fact is of great importance in the diagnosis and monitoring of varicocele.
The images of halos generated with Halosperm® are highly contrasted and can be evaluated precisely using conventional or fluorescent microscopy. The tails of the spermatozoa are preserved, so it is possible to discriminate them from other cell types that might be present in the ejaculate, such as leukocytes. In addition, Halosperm® allows the visualisation of spermatozoa that contain highly degraded DNA compared to other types of less aggressive damage. This fact is of great importance in the diagnosis and monitoring of varicocele.
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